The creation of the Signia line to combat chronoaging of the skin is the result of 50 years of AMOREPACIFIC research in the field of plant stem cells. The eye cream contains stem cells from narcissus bulbs, stem cells from narcissus flowers, STEM-CORD complex, liquidum™ complex. Stem cell extract from narcissus bulbs and flowers activates the natural mechanisms of cell protection from aggressive environmental factors (dry air, sun, extreme temperatures, wind). Narcissus extract is obtained during the period of anabiosis (temporary dormancy) from daffodil bulbs. It was observed that the extract slows down cell proliferation, increasing their vitality. IBR-Dormin™ is a component extracted from narcissus tuber extract. IBR-Dormin™ is able to slow down the process of age-related cell proliferation (division), which, according to Hayflick's theory, can significantly slow down the aging process of the skin. Among natural biological substances that can resist temporary changes in cells, there is a separate class of natural phytohormones, which are called “dormines”. Dormins are growth inhibitors that encourage the plant to enter a dormant state. IBR-Dormin is a substance extracted from the natural extract of the Narcissus bulb during the dormant period. A series of scientific studies have confirmed the effect of IBR-Dormin, aimed at increasing the cell cycle (the period of cell life until the next division). An additional period of time allows the cells to acquire full protective functions for the subsequent transfer of favorable DNA (the process of acquiring unique properties inherent specifically to skin cells occurs). The natural slowdown of the proliferation process leads to the preservation of the original properties of cells. Narcissus bulb extract helps activate the natural mechanisms of cell protection from aggressive environmental factors (dry air, sun, extreme temperatures, wind).